BioSAXS-2000 nano FOR PHARMACEUTICALS

FEATURES & BENEFITS

• High-Flux 2D Kratky Small Angle X-ray Scattering System with WAXS capabilities.
• Can be used for solid samples, powder, gels, creams, and liquids.
• Unique focusing 2D Kratky optics with photon counting 2D detector gives high X-ray flux, short path length and fast measurement times.
• Observation of structure and microstructure for organic systems on a nano meter length scale.
• Characterization of solution phase behavior (agglomeration, self-assembly, disassociation.) for small molecule and biologics.
• Change in protein shape and aggregation behavior in solution with formulation and temperature changes.
• Pre-cursor crystallization screen for large molecules and proteins.
• Rapid screening of molecular weight, radius of gyration, size, folding behavior and molecular modeling for mono-dispersed large molecule solutions.
• Meso-phase (liquid crystal) identification, characterization, and non-ambient behavior.
• Excipient micro-structure formation and encapsulation for formulated products.
• Formation of nano structures and self-assembly (micelles and lipids) as a function of temperature and formulation.
• Nano meter heterogeneity in amorphous systems, gels and creams.
• Multiple sample stages to suit application:
  • Heating and Cooling stages
  • Automatic sample changers (liquid, solid and paste/gel)
  • Bulk sample stage
  • Rotation stage
  • Paste/gel sample stage for viscous samples
  • Isolation cells (for reactive or toxic materials).
  • High throughput 96-well plate handling for solution samples
  • WAXS option