Pharmalytical Insights

The Pharma Lab Show: The Powerful Benefits of Pairwise Distribution Function

Written by Simon Bates, Ph. D. | Nov 10, 2021 10:30:26 PM

 

Pairwise distribution function (PDF) can be a very useful tool for pharmaceutical professionals, especially when characterizing active pharmaceutical ingredients.

Using total diffraction and PDF analysis you can confirm — and even solve — the molecular structure of new materials in non-crystalline states in addition to characterizing the local molecular order.

In this episode, Simon Bates, VP of Science and Technology at Rigaku, shares why PDF and total diffraction combined together are so powerful in confirming molecular structures and why they are opening the door to new materials in pharmaceutics.

We discuss:

  • - The uses for PDF
  • - The challenges of total diffraction and PDF
  • - Keeping track of advances in PDF approaches

Check out these resources we mentioned during the podcast:

Learn more about Atomic Pair Distribution Function from Simon Bates here.
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